Novel poly(amino ester)s obtained from Michael addition polymerizations of trifunctional amine monomers with diacrylates: safe and efficient DNA carriers.

نویسندگان

  • Ye Liu
  • Decheng Wu
  • Yuexia Ma
  • Guping Tang
  • Shu Wang
  • Chaobin He
  • Taishung Chung
  • Suathong Goh
چکیده

Novel biodegradable poly(amino ester)s containing secondary and tertiary amines in the backbones were obtained from the Michael addition polymerizations of trifunctional amine monomers with diacrylates, and showed high transfection efficiency for the delivery of DNA comparable to those of polyethylenimine (PEI) and low cytotoxicity.

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عنوان ژورنال:
  • Chemical communications

دوره 20  شماره 

صفحات  -

تاریخ انتشار 2003